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November 27, 2021

Transit Bipartition: An Attractive Revision Alternative When Sleeve Gastrectomy Fails

Transit Bipartition is a kind of gastric bypass procedures but includes a sleeve gastrectomy. For patients that couldn’t lose adequate weight or regain weight after laparoscopic sleeve gastrectomy (LSG), second step revisional bariatric surgical treatment in the form of transportation bipartition is an effective next step, say clinicians in Germany.

In Annals of Surgery Open, they note that "Laparoscopic sleeve gastrectomy has obtained global acceptance as a first-line bariatric surgical procedure for the treatment of morbid obesity. Nevertheless, long-lasting results vary with reported rates of primary failure or weight regain between 25% and 50% at five years depending on the definitions used."

Transit bipartition (TB) may be "an attractive revisional surgery strategy after LSG given the formidable weight reductions of 27% overall weight reduction at one year as a first-line intervention," state Dr. Markus Reiser with Klinikum-Vest GmbH, Paracelsus-klinik Marl, in Marl, as well as coworkers.

In their paper, they report results in 100 morbidly obese patients (79 ladies) who undertook revisional TB for inadequate weightloss or weight regain after LSG, with follow-up bent on twelve month.

Mean BMI before LSG was 49.9 kg/m2 as well as reduced to an optimum of 32.7 kg/m2 at 22.1 months after LSG, representing an excess-weight loss of 70.0%.

The mean time in between sleeve and transit bipartition was 52.2 months, at which time imply BMI had enhanced to 37.6 kg/m2, representing 49.4% excess-weight loss.

Following TB, BMI lowered continually to 31.4 kg/m2 after twelve month with an equivalent increase in excess-weight loss to 74.7% and overall weight reduction reaching 36.3%.

Nevertheless, the length of the common channel (CC) had a considerable effect on TB results; after 12 months, weight loss was significantly higher for CC length of 250 centimeters versus 300 cm (BMI, 29.4 vs. 33.0 kg/m2, P= 0.002; as well as excess-weight loss of 79.8% vs. 70.4%; P= 0.009).

" Improvement of comorbidities was observed in a high percentage of people. Major complications were observed in 3% of people and handled without fatalities," the medical professionals report.

In addition to weight management, a lot of people saw resolution of obesity-related comorbidities such as high blood pressure, obstructive sleep apnea as well as type-2 diabetes, in addition to stubborn or new onset signs and symptoms of gastroesophageal reflux condition (GERD).

" Complete satisfaction concerning the mixed endpoints of weight loss and resolution of reflux symptoms was high with 83% of clients reporting to be extremely or on the whole satisfied," the medical professionals record.

A power of this study is the big number of patients from a prospective windows registry, every one of whom were followed up at year.

A constraint is the detailed style which does not permit straight contrast of TB to other RBS treatments. In addition, the one year follow-up is short, "leaving the verification of a long term influence unanswered."

SOURCE: https://bit.ly/3q3OsPP Annals of Surgery Open, on the internet October 1, 2021. https://pubmed.ncbi.nlm.nih.gov/23532991https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497590

In Summary:

Transit bipartition is a type of bariatric surgery procedure used for weight loss and metabolic improvement in obese patients. Here's a concise summary:

  1. Procedure overview:
    Transit bipartition is a malabsorptive and restrictive procedure that involves dividing the stomach into two parts and rerouting a portion of the small intestine.
  2. Key components:
  • Vertical sleeve gastrectomy: The stomach is reduced in size by creating a sleeve-shaped pouch.
  • Intestinal bypass: A portion of the small intestine is connected to the newly created stomach sleeve, creating a shortcut for food transit.
  • Preservation of intestinal continuity: Unlike some other bariatric procedures, transit bipartition maintains the natural continuity of the intestine.
  1. Mechanism of action:
  • Restrictive effect: The smaller stomach limits food intake.
  • Malabsorptive effect: The intestinal rerouting reduces nutrient absorption.
  • Hormonal changes: The procedure affects gut hormones, potentially improving metabolic health.
  1. Potential benefits:
  • Significant weight loss
  • Improvement in obesity-related comorbidities (e.g., type 2 diabetes, hypertension)
  • Preservation of some nutrient absorption due to maintained intestinal continuity
  1. Considerations:
  • Relatively new procedure compared to more established bariatric surgeries
  • Long-term outcomes and potential complications still being studied
  • May require close nutritional monitoring and supplementation

Transit bipartition aims to combine the benefits of restrictive and malabsorptive approaches while potentially reducing some of the nutritional risks associated with more extensive intestinal bypass procedures.

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